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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCLK1
All Species:
23.33
Human Site:
S590
Identified Species:
46.67
UniProt:
O15075
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15075
NP_004725.1
740
82224
S590
G
F
P
P
F
R
G
S
G
D
D
Q
E
V
L
Chimpanzee
Pan troglodytes
XP_522657
872
96662
S733
G
F
P
P
F
R
G
S
G
D
D
Q
E
V
L
Rhesus Macaque
Macaca mulatta
XP_001082020
783
85228
E611
G
F
P
P
F
R
S
E
N
N
L
Q
E
D
L
Dog
Lupus familis
XP_849124
740
82175
S590
G
F
P
P
F
R
G
S
G
D
D
Q
E
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLM8
756
84135
S606
G
F
P
P
F
R
G
S
G
D
D
Q
E
V
L
Rat
Rattus norvegicus
Q5MPA9
767
83998
E609
G
F
P
P
F
R
S
E
N
N
L
Q
E
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511397
792
88039
S651
G
F
P
P
F
R
G
S
G
D
D
Q
E
V
L
Chicken
Gallus gallus
XP_417099
1048
115422
S896
G
F
P
P
F
R
G
S
G
D
D
Q
E
V
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q501V0
422
47914
S290
V
I
S
Y
I
L
L
S
G
T
M
P
F
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7PLI7
748
82953
I599
M
G
I
V
H
R
D
I
K
P
E
N
L
L
V
Honey Bee
Apis mellifera
XP_394386
670
74883
Y537
E
R
I
L
S
G
Q
Y
D
F
R
S
P
F
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189418
661
74296
L529
D
G
T
K
S
L
K
L
G
D
F
G
L
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.4
65.3
99.8
N.A.
96.4
65.3
N.A.
86.2
63.7
N.A.
24.7
N.A.
29.8
41
N.A.
52.3
Protein Similarity:
100
80.1
77.5
99.8
N.A.
97.3
77.8
N.A.
88
64.9
N.A.
35
N.A.
47.5
57.9
N.A.
65.9
P-Site Identity:
100
100
60
100
N.A.
100
60
N.A.
100
100
N.A.
13.3
N.A.
6.6
0
N.A.
13.3
P-Site Similarity:
100
100
66.6
100
N.A.
100
66.6
N.A.
100
100
N.A.
13.3
N.A.
26.6
0
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
9
0
9
59
50
0
0
17
9
% D
% Glu:
9
0
0
0
0
0
0
17
0
0
9
0
67
9
0
% E
% Phe:
0
67
0
0
67
0
0
0
0
9
9
0
9
9
0
% F
% Gly:
67
17
0
0
0
9
50
0
67
0
0
9
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
17
0
9
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
9
0
0
9
0
9
0
0
0
0
0
0
% K
% Leu:
0
0
0
9
0
17
9
9
0
0
17
0
17
9
67
% L
% Met:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
17
17
0
9
0
0
0
% N
% Pro:
0
0
67
67
0
0
0
0
0
9
0
9
9
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
67
0
0
0
% Q
% Arg:
0
9
0
0
0
75
0
0
0
0
9
0
0
0
0
% R
% Ser:
0
0
9
0
17
0
17
59
0
0
0
9
0
0
0
% S
% Thr:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
9
% T
% Val:
9
0
0
9
0
0
0
0
0
0
0
0
0
50
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _